Endocytosis - an important mechanism for path finding of cells during development of the nervous system
Research report (imported) 2003 - Max Planck Institute of Neurobiology
During development of the nervous system each neuron is generating a long process called axon and several short, widely ramified structures called dendrites. Each of those axons is developing a growth cone from which foot- and tentacle-like extensions are protruding (lamellipodia and filopodia). The neurons are thus able to channel through tissue or contact other nerve cells to build a complete nervous system. Other cells that are contacted by a migrating neuron are leading the way, such that they first bind to the respective neuron and reject it shortly after.