Publications of Christopher Linington

Ng, J. K. M.; Malotka, J.; Kawakami, N.; Derfuss, T.; Khademi, M.; Olsson, T.; Linington, C.; Odaka, M.; Tackenberg, B.; Pruess, H. et al.; Schwab, J. M.; Harms, L.; Harms, H.; Sommer, C.; Rasband, M. N.; Eshed-Eisenbach, Y.; Peles, E.; Hohlfeld, R.; Yuki, N.; Dornmair, K.; Meinl, E.: Neurofascin as a target for autoantibodies in peripheral neuropathies. Neurology 79 (23), pp. 2241 - 2248 (2012)

Derfuss, T.; Linington, C.; Hohlfeld, R.; Meinl, E.: Axo-glial antigens as targets in multiple sclerosis: Implications for axonal and grey matter injury. Journal of Molecular Medicine 88 (8), pp. 753 - 761 (2010)

Meinl, E.; Derfuss, T.; Linington, C.: Identifying targets for autoantibodies in CNS inflammation: Strategies and achievements. Clinical and Experimental Neuroimmunology 1 (2), pp. 47 - 60 (2010)

Bourquin, C.; van der Haar, M. E.; Anz, D.; Sandholzer, N.; Neumaier, I.; Endres, S.; Skerra, A.; Schwab, M. E.; Linington, C.: DNA vaccination efficiently induces antibodies to Nogo-A and does not exacerbate experimental autoimmune encephalomyelitis. European Journal of Pharmacology 588 (1), pp. 99 - 105 (2008)

Breithaupt, C.; Schäfer, B.; Pellkofer, H.; Huber, R.; Linington, C.; Jacob, U.: Demyelinating myelin oligodendrocyte glycoprotein-specific autoantibody response is focused on one dominant conformational epitope region in rodents. Journal of Immunology 181 (2), pp. 1255 - 1263 (2008)

Mathey, E. K.; Derfuss, T.; Storch, M. K.; Williams, K. R.; Hales, K.; Woolley, D. R.; Al-Hayani, A.; Davies, S. N.; Rasband, M. N.; Olsson, T. et al.; Moldenhauer, A.; Velhin, S.; Hohlfeld, R.; Meinl, E.; Linington, C.: Neurofascin as a novel target for autoantibody-mediated axonal injury. Journal of Experimental Medicine 204 (10), pp. 2363 - 2372 (2007)

Wekerle, H.; Linington, C.: Organ specific autoantigens and the autoreactive T cell repertoire: The case of myelin oligodendrocyte glycoprotein. European Journal of Immunology 36 (3), pp. 512 - 515 (2006)

Aboul-Enein, F.; Bauer, J.; Klein, M.; Schubart, A.; Flügel, A.; Ritter, T.; Kawakami, N.; Siedler, F.; Linington, C.; Wekerle, H. et al.; Lassmann, H.; Bradl, M.: Selective and antigen-dependent effects of myelin degeneration on central nervous system inflammation. Journal of Neuropathology and Experimental Neurology 63 (12), pp. 1284 - 1296 (2004)

Guggenmos, J.; Schubart, A. S.; Ogg, S.; Andersson, M.; Olsson, T.; Mather, I. H.; Linington, C.: Antibody cross-reactivity between myelin oligodendrocyte glycoprotein and the milk protein butyrophilin in multiple sclerosis. Journal of Immunology 172 (1), pp. 661 - 668 (2004)

Kawakami, N.; Lassmann, S.; Li, Z. X.; Odoardi, F.; Ritter, T.; Ziemssen, T.; Klinkert, W. E. F.; Ellwart, J. W.; Bradl, M.; Krivacic, K. et al.; Lassmann, H.; Ransohoff, R. M.; Volk, H. D.; Wekerle, H.; Linington, C.; Flügel, A.: The activation status of neuroantigen-specific T cells in the target organ determines the clinical outcome of autoimmune encephalomyelitis. Journal of Experimental Medicine 199 (2), pp. 185 - 197 (2004)

Mead, R. J.; Neal, J. W.; Griffiths, M. R.; Linington, C.; Botto, M.; Lassmann, H.; Morgan, B. P.: Deficiency of the complement regulator CD59a enhances disease severity, demyelination and axonal injury in murine acute experimental allergic encephalomyelitis. Laboratory Investigation 84 (1), pp. 21 - 28 (2004)

Pellkofer, H.; Schubart, A. S.; Hoftberger, R.; Schutze, N.; Pagany, M.; Schuller, M.; Lassmann, H.; Hohlfeld, R.; Voltz, R.; Linington, C.: Modelling paraneoplastic CNS disease: T-cells specific for the onconeuronal antigen PNMA1 mediate autoimmune encephalomyelitis in the rat. Brain 127, pp. 1822 - 1830 (2004)

Bourquin, C.; Schubart, A.; Tobollik, S.; Mather, I.; Ogg, S.; Liblau, R.; Linington, C.: Selective unresponsiveness to conformational B cell epitopes of the myelin oligodendrocyte glycoprotein in H-2(b) mice. Journal of Immunology 171 (1), pp. 455 - 461 (2003)

Breithaupt, C.; Schubart, A.; Zander, H.; Skerra, A.; Huber, R.; Linington, C.; Jacob, U.: Structural insights into the antigenicity of myelin oligodendrocyte glycoprotein. Proceedings of the National Academy of Sciences of the United States of America 100 (16), pp. 9446 - 9451 (2003)

Gold, R.; Linington, C.: Glatiramer acetate treatment in Devic's neuromyelitis optica - Reply. Brain 126, p. E1 - E1 (2003)

Pagany, M.; Jagodic, M.; Bourquin, C.; Olsson, T.; Linington, C.: Genetic variation in myelin oligodendrocyte glycoprotein expression and susceptibility to experimental autoimmune encephalomyelitis. Journal of Neuroimmunology 139 (1-2), pp. 1 - 8 (2003)

Pagany, M.; Jagodic, M.; Schubart, A.; Pham-Dinh, D.; Bachelin, C.; van Evercooren, A. B.; Lachapelle, F.; Olsson, T.; Linington, C.: Myelin oligodendrocyte glycoprotein is expressed in the peripheral nervous system of rodents and primates. Neuroscience Letters 350 (3), pp. 165 - 168 (2003)

Abdul-Majid, K. B.; Stefferl, A.; Bourquin, C.; Lassmann, H.; Linington, C.; Olsson, T.; Kleinau, S.; Harris, R. A.: Fc receptors are critical for autoimmune inflammatory damage to the central nervous system in experimental autoimmune encephalomyelitis. Scandinavian Journal of Immunology 55 (1), pp. 70 - 81 (2002)

Andersson, M.; Yu, M.; Soderstrom, M.; Weerth, S.; Baig, S.; Linington, C.; Solders, G.; Link, H.: Multiple MAG peptides are recognized by circulating T and B lymphocytes in polyneuropathy and multiple sclerosis. European Journal of Neurology 9 (3), pp. 243 - 251 (2002)

Gold, R.; Linington, C.: Devic's disease: Bridging the gap between laboratory and clinic. Brain 125, pp. 1425 - 1427 (2002)

Popovic, N.; Schubart, A.; Goetz, B. D.; Zhang, S. C.; Linington, C.; Duncan, I. D.: Inhibition of autoimmune encephalomyelitis by a tetracycline. Annals of Neurology 51 (2), pp. 215 - 223 (2002)

Storch, M. K.; Weissert, R.; Stefferl, A.; Birnbacher, R.; Wallstrom, E.; Dahlman, I.; Ostensson, C. G.; Linington, C.; Olsson, T.; Lassmann, H.: MHC gene related effects on microglia and macrophages in experimental autoimmune encephalomyelitis determine the extent of axonal injury. Brain Pathology 12 (3), pp. 287 - 299 (2002)

Egg, R.; Reindl, M.; Deisenhammer, F.; Linington, C.; Berger, T.: Anti-MOG and anti-MBP antibody subclasses in multiple sclerosis. Multiple Sclerosis Journal 7 (5), pp. 285 - 289 (2001)

Hackstein, H.; Bitsch, A.; Bohnert, A.; Hofmann, H.; Weber, F.; Ohly, A.; Linington, C.; Maurer, M.; Poser, S.; Rieckmam, P. et al.; Bein, G.: Analysis of interleukin-4 receptor α chain variants in multiple sclerosis. Journal of Neuroimmunology 113 (2), pp. 240 - 248 (2001)

Iglesias, A.; Bauer, J.; Litzenburger, T.; Schubart, A.; Linington, C.: T- and B-cell responses to myelin oligodendrocyte glycoprotein in experimental autoimmune encephalomyelitis and multiple sclerosis. Glia 36 (2), pp. 220 - 234 (2001)

Stefferl, A.; Schubart, A.; Storch, M.; Amini, A.; Mather, I.; Lassmann, H.; Linington, C.: Butyrophilin, a milk protein, modulates the encephalitogenic T cell response to myelin oligodendrocyte glycoprotein in experimental autoimmune encephalomyelitis. The Journal of Immunology 165 (5), pp. 2859 - 2865 (2000)

Reindl, M.; Linington, C.; Brehm, U.; Egg, R.; Dilitz, E.; Deisenhammer, F.; Poewe, W.; Berger, T.: Antibodies against the myelin oligodendrocyte glycoprotein and the myelin basic protein in multiple sclerosis and other neurological diseases: A comparative study. Brain 122, pp. 2047 - 2056 (1999)

Bauer, J.; Bradl, M.; Hickey, W. F.; Forss-Petter, S.; Breitschopf, H.; Linington, C.; Wekerle, H.; Lassmann, H.: T-cell apoptosis in inflammatory brain lesions - Destruction of T cells does not depend on antigen recognition. American Journal of Pathology 153 (3), pp. 715 - 724 (1998)

Litzenburger, T.; Fässler, R.; Bauer, J.; Lassmann, H.; Linington, C.; Wekerle, H.; Iglesias, A.: B lymphocytes producing demyelinating autoantibodies: Development and function in gene-targeted transgenic mice. Journal of Experimental Medicine 188 (1), pp. 169 - 180 (1998)

Storch, M. K.; Stefferl, A.; Brehm, U.; Weissert, R.; Wallstrom, E.; Kerschensteiner, M.; Olsson, T.; Linington, C.; Lassmann, H.: Autoimmunity to myelin oligodendrocyte glycoprotein in rats mimics the spectrum of multiple sclerosis pathology. Brain Pathology 8 (4), pp. 681 - 694 (1998)